8‘50 a medicine-X is developed to treat lung cancer But it effects just a few month and some genes resist the drug. Then scientists found MED12 and two genes resist the X by disabling mutation. So DR.. wants to block TGF by using MED12 to solve the problem, but MED12 interfere other effective medicines. the work is a long process.
There has been a new drug X as a treatment for a certain kind of cancer.
However, like many other treatments for cancers, its effect does not last long. As known, cancer cells can be repressed for only a period but start to mutate new cells that cannot be blocked by X.
Scientists are eagerly trying to figure out a solution to the resistant mutations. RB in Netherlands Cancer Institute has run some tests to find out why mutations appear after a while. And he came up with some crucial findings using hairpin.
RB found MED 12, which reduces the sensitivity to X and thus stops the effects of X.
He also found other two mutations of genes that helps MED 12 to work.
Moreover, he found out that TGB beta 8 is responsible for mutating the surface of cells thus making the X useless.
Other 3 groups have also gain progress in the same field. These are only experimental results that needs to be applied to clinical treatments. Once they are altered to fit clinical treatments, the effective period of other drugs(I and T for lung cancers, Z for melenoma and anN for spleens(?)) can also be prolonged.
第一个忘按start了， 1‘52 1’43 1‘32 1’36 越障7‘04 1.A medicine called X was discovered to the control cancer. 2.The fact that double-standard RNA exists mostly in the virus can help to detect the cells which should be destroyed. 3.有三个什么东西，one transcribe DNA to RNA, the other two can maintain the structure of chromosome. 读的时候觉得还挺有条理，全读完了就什么都想不起来了
-The scientists try to find the treatment for cancer, and they found that a medicine called X can cure the lung cancer. However, most drugs only can be used once to prohibit the genes growth of cancer. Normally, patients will come back the second year when the genes grow again, and meanwhile, the tumor will grow back. - Dr. Bernard found the RNA, a smaller molecule than DNA, exists in the virus and also are able to send messages to other genes. This finding will be successful if such RNA can resist and function well to inhibit the genes of tumor. So it's necessary to synthesize as many genes as possible to find out this molecule, and the modern medical technology can achieve this easily. - Then Dr. Bernard finally found three molecules which probably cure the cancer. One of them is called MED-12 from 20000 combined RNA genes, and such molecule can actually resist the tumor genes although it may not stopped its growth. And the other two also help to treat the lung cancer. - The finding of MED-12 from Dr. Bernard is just Vanguard, but there are another three groups of scientists in Boston also follow this experiment, and their findings are also meaningful, they claimed that this molecule might solve the problems of cancer which has been encountered for a long time. - The experiments are still ongoing, certainly there will be more failures, so there will be a long way to go.
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发表于 2011-9-30 10:17:20
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