A drug X to treat lung cancer by blocking the growth of T**.
Disadvantage: because of the mutation in T**, the cancer continue and the drug doesn’t have desirable effect.
Problem: Difficult to detect undesirable mutation.
Dr.B finds that undesirable message form RNA into double-strand, while normal mammal’s RNA is single-strand, the fact which helps detect undesirable mutation.
Dr.B finds 3 genes messages (M12+other 2) are related to the resistance of drug.
Dr.B invents an experimental drug to block TGF in M12. The drug doesn’t treat cancer directly but interferes M12 help X work.
The work of B is promising .
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