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Nearly a century ago, biologists found that if they
separated an invertebrate animal embryo into two parts
at an early stage of its life, it would survive and develop
as two normal embryos. This led them to believe that the
(5) cells in the early embryo are undetermined in the sense
that each cell has the potential to develop in a variety of
different ways. Later biologists found that the situation
was not so simple. It matters in which plane the embryo
is cut. If it is cut in a plane different from the one used
(10) by the early investigators, it will not form two whole
embryos.
A debate arose over what exactly was happening.
Which embryo cells are determined, just when do they218
become irreversibly committed to their fates, and what
(15) are the “morphogenetic determinants” that tell a cell
what to become? But the debate could not be resolved
because no one was able to ask the crucial questions
in a form in which they could be pursued productively.
Recent discoveries in molecular biology, however, have
(20) opened up prospects for a resolution of the debate.
Now investigators think they know at least some of the
molecules that act as morphogenetic determinants in
early development. They have been able o show that,
in a sense, cell determination begins even before an egg
(25) is fertilized.
Studying sea urchins, biologist Paul Gross found
that an unfertilized egg contains substances that function
as morphogenetic determinants. They are located
in the cytoplasm of the egg cell; i.e., in that part of the
(30) cell’s protoplasm that lies outside of the nucleus. In the
unfertilized egg, the substances are inactive and are not
distributed homogeneously. When the egg is fertilized,
the substances become active and, presumably, govern
the behavior of the genes they interact with. Since the
(35) substances are unevenly distributed in the egg, when the
fertilized egg divides, the resulting cells are different
from the start and so can be qualitatively different in
their own gene activity.
The substances that Gross studied are maternal
(40) messenger RNA’s --products of certain of the maternal
genes. He and other biologists studying a wide variety
of organisms have found that these particular RNA’s
direct, in large part, the synthesis of histones, a class
of proteins that bind to DNA. Once synthesized, the
(45) histones move into the cell nucleus, where section of
DNA wrap around them to form a structure that resembles
beads, or knots, on a string. The beads are DNA
segments wrapped around the histones; the string is the
intervening DNA. And it is the structure of these beaded
(50) DNA strings that guides the fate of the cells in which
they are located.
25. It can be inferred from the passage that the morphogenetic determinants present in the early embryo are
(A) located in the nucleus of the embryo cells
(B) evenly distributed unless the embryo is not developing normally
219
(C) inactive until the embryo cells become irreversibly committed to their final function
(D) identical to those that were already present in the unfertilized egg
(E) present in larger quantities than is necessary for the development of a single individual
25.
E is the best answer.
The second and third paragraphs of the passage indicate that morphogenetic determinants are substances in the embryo that are activated after the egg has been fertilized and that “tell a cell
what to become” (lines 21-23). If, as the author asserts in the first paragraph, biologists have
succeeded in dividing an embryo into two parts, each of which survives and develops into a
normal embryo, it can be concluded that the quantity of morphogenetic determinants in the early
embryo is greater than that required for the development of a single individual.
这题版面上所有的讨论都看了，可是我怎么觉得大家都没讲清楚啊？
红线部分
生物学家成功的把一个胚胎分成了两部分，且这两部分都发展成了一个独立的胚胎，这就能得出结论：morphogenetic determinants在早期胚胎中得数量远远多于发展一个独立胚胎所需数量？
这哪跟哪啊？
怎么推导得啊？是否中间省略了什么步骤？ | 
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发表于 2005-1-17 00:27:00
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