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PASSAGE 36 * Protein synthesis begins when the gene encoding a protein is activated. The gene's sequence of nucleotides is transcribed into a molecule of messenger RNA mRNA), which reproduces the information contained in that 5) sequence. Transported outside the nucleus to the cyto- plasm, the mRNA is translated into the protein it encodes by an organelle known as a ribosome, which strings together amino acids in the order specified by the sequence of elements in the mRNA molecule. Since the 10) amount of mRNA in a cell determines the amount of the corresponding protein, factors affecting the abundance of mRNA's play a major part in the normal functioning of a cell by appropriately regulating protein synthesis. For example, an excess of certain proteins can cause cells 15) to proliferate abnormally and become cancerous; a lack of the protein insulin results in diabetes. * Biologists once assumed that the variable rates at which cells synthesize different mRNA's determine the quantities of mRNA's and their corresponding proteins 20) in a cell. However, recent investigations have shown that the concentrations of most mRNA's correlate best, not with their synthesis rate, but rather with the equally vari- able rates at which cells degrade the different mRNA's in their cytoplasm. If a cell degrades both a rapidly and 25) a slowly synthesized mRNA slowly, both mRNA's will accumulate to high levels. * An important example of this phenomenon is the development of red blood cells from their unspecialized parent cells in bone marrow. For red blood cells to accu- 30) mulate sufficient concentrations of hemoglobin which transports oxygen) to carry out their main function, the cells' parent cells must simultaneously produce more of the constituent proteins of hemoglobin and less of most other proteins. To do this, the parent cells halt synthesis 35) of nonhemoglobin mRNA's in the nucleus and rapidly degrade copies of the nonhemoglobin mRNA's remaining in the cytoplasm. Halting synthesis of mRNA alone would not affect the quantities of proteins synthesized by the mRNA's still existing in the cytoplasm. Biologists now 40) believe that most cells can regulate protein production most efficiently by varying both mRNA synthesis and degradation, as developing red cells do, rather than by just varying one or the other.
8. The passage suggests that a biologist who detected highlevels of two proteins in a certain type of cell would belikely to consider which of the following as a possibleexplanation? (A) The rate of mRNA degradation for one of theproteins increases as this type of cell develops amore specialized function. (B) The two proteins are most likely constituents of acomplex substance supporting the cells' specializedfunction. (C) The cells are likely to proliferate abnormally andpossibly become cancerous due to the levels of theseproteins. (D) The mRNA's for both proteins are being degradedat a low rate in that type of cell. (E) The mRNA's for the two proteins are beingsynthesized at identical rates in that type of cell.
问,我不太明白,为什么C不对呢?高亮的部分不是C的意思吗? |
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