Recently, an internal science team at a U.S.-based major biotechnology firm was assigned to develop a method for rapid and simple detection of DNA sequences in unconventional field settings. Their mission was to produce a DNA sequencing test that was cost effective, robust, and operable in extreme field conditions. After several months of effort, the team in consultation with company experts concluded that no viable solution existed for their problem. Since solving the problem was of critical importance for the firm, management decided to break from convention and the disclose the specifics of the problem to a large group of unknown "outside" scientists requesting a solution in return for substantial prize money. In a four-week period of time, over 574 scientists investigated the problem statement and forty-two of them submitted potential solutions for considerations. The winning solution was proposed by a scientist from Finland who did not work in this field. The solution involved the novel application of an existing methodology to the problem at hand. Besides solving the problem, the solution information opened up a new knowledge domain for future investigations and resulted in a valuable patent for the firm. This case example illustrates how the disclosure and wide dispersion of scientific problem information allows R&D organizations to access a broader range of scientific knowledge, and can help accelerate internal and proprietary research efforts.
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