OG－164

mariebleu

164. Useful protein drugs, such as insulin, must still be administered by the cumbersome

procedure of injection under the skin. If proteins are taken orally, they are digested and

cannot reach their target cells. Certain nonprotein drugs, however, contain chemical bonds

that are not broken down by the digestive system. They can, thus, be taken orally.

The statements above most strongly support a claim that a research procedure that

successfully accomplishes which of the following would be beneficial to users of protein

drugs?

(A) Coating insulin with compounds that are broken down by target cells, but whose

chemical bonds are resistant to digestion

(B) Converting into protein compounds, by procedures that work in the laboratory, the

nonprotein drugs that resist digestion

(C) Removing permanently from the digestive system any substances that digest proteins

(D) Determining, in a systematic way, what enzymes and bacteria are present in the normal

digestive system and whether they tend to be broken down within the body

(E) Determining the amount of time each nonprotein drug takes to reach its target cells.

164.

Coating insulin as described in choice A, the best answer, would benefit protein-drug users by

removing the obstacle identified in the passage that prevents protein drugs, such as insulin,

from being taken orally. The insulin would become available to the target cells, since these

cells would break down the coating.

Converting nonprotein drugs into protein compounds (choice B) would necessitate

administration by injection, benefiting neither their users nor users of protein drugs. If removing

substances that digest proteins (choice C) enabled protein drugs to be taken orally, it would be

at the expense of normal digestive function. The breakdown of normally occurring bacteria and

enzymes (choice D) and the activity of nonprotein drugs (choice E) are irrelevant to the

problems associated with protein drugs.

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在A和C当中我开始还是选择了C，因为觉得A在说insulin，但是protein drugs有很多种啊，insulin只是其中的一种，如何能代表在其他任何一种protein drugs上都能获得相同的作用呢。而C，OG解释的很清楚，说这样是要以牺牲正常的消化功能为代价的，违背了题干说到的beneficial to的意思。对于A，偶错在哪里了捏？牛牛们帮忙。

yanginottawa

不是什么nn，

我觉得做题不能自己延伸，联想题干以外的东西，既然说了insulin，那就用它，不用过多考虑其他种蛋白。而这道题读懂了内容就应该能做了，读题总是占用很长时间的。

magieus

以下是引用mariebleu在2005-11-17 13:25:00的发言：

在A和C当中我开始还是选择了C，因为觉得A在说insulin，但是protein drugs有很多种啊，insulin只是其中的一种，如何能代表在其他任何一种protein drugs上都能获得相同的作用呢。而C，OG解释的很清楚，说这样是要以牺牲正常的消化功能为代价的，违背了题干说到的beneficial to的意思。对于A，偶错在哪里了捏？牛牛们帮忙。

我也是因为同样的原因而想过可能A不会是答案，但其它没有好选的，所以最后还是选了A。这是一道归纳题，且不是“推理链”式的，所以只要符合文章的信息就行了吧。

gonghao

A是说对I进行包衣吧

我的问题是B，先做成衍生物，到达target药物，还原成原形也应该可以啊