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- 2020-2-24
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- 1970-1-1
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P1:介紹VD缺乏的壞處不止軟骨症
-VD believed to prevent rickets
-Once milk+VD, rickets disappear, problem of VD deficiency solved.
-MFH: rickets=the tip of VD deficiency iceberg (meaning there are other problems caused by VD deficiency)
P2:VD還能防癌及掌管200個基因，包含負責細胞生老病死的
-experiment:VD activation—> prostate regulate own growth&prevent cancer
-VD controls 200 genes, including ones responsible for cell proliferation, differentiation, and death
P3:實驗發現VD可以抗癌
-VD=cancer prevention
-results of 4yr trial—> women took VD had 60% lower risk of developing cancers
P4:VD影響感染的抵抗性
-VD status— vulnerability to infections
-AA need more sun than C to make VD, AA suffered from increased risk of T
-possible link: 巨噬細胞碰到TB b會刺激VD的轉換，把VD轉換成active form來製造peptide去破壞TB b，因此若VD不夠則巨噬細胞無法激活VD去啟動這一係列反應
-similar w other infectious agents, maybe influenza virus
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发表于 2022-10-12 21:49:18
