Which of the following most logically completes the passage?

Appendicitis (inflammation of the appendix) is potentially fatal; consequently, patients with symptoms strongly suggesting appendicitis almost always have their appendix removed. The appropriate surgery is low-risk but performed unnecessarily in about 20 percent of all cases. A newly developed internal scan for appendicitis is highly accurate, producing two misdiagnoses for every 98 correct diagnoses. Clearly, using this test, doctors can largely avoid unnecessary removals of the appendix without, however, performing any fewer necessary ones than before, since ______.

• Athe patients who are correctly diagnosed with this test as not having appendicitis invariably have medical conditions that are much less serious than appendicitis  
• Bthe misdiagnoses produced by this test are always instances of attributing appendicitis to someone who does not, in fact, have it  
• Call of the patients who are diagnosed with this test as having appendicitis do, in fact, have appendicitis  
• Devery patient who is diagnosed with this test as having appendicitis has more than one of the symptoms generally associated with appendicitis  
• Ethe only patients who are misdiagnosed using this test are patients who lack one or more of the symptoms that are generally associated with appendicitis