【每日综合训练—60系列】【60-03】科技

sijingbo

Time 2    1'52''
Using off-label cancer drugs provide no benefits
Time 3    1'17''
US cancer institute plan to start personalized cancer trials  . If it is beneficial,regardless of whether the drugs have been approved, it will pose a challenge.
Time 4   1'25''
A kind of nanoparticles will have advantages  1)evade detection and exploit natural properties    2) more likely to interact
Time 5   1'21''
The particle's cloaking ability is doubted  and the team still need to test the particle's ability.
Time 6 + rest     1'12''
A 8.1 earthquake happened in Chile and it led to a tusami.The earthquake damaged some telescope and experts worries that a bigger one may happen in the future.

Obstacle     5'00
VW was accused of installing software that designed to pass federal emissions tests but releaseing higher levels.EPA didn't recall the cars and said the cars remain safe.VW vehicles were questioned earlier time cuz they were found higher emission in Europe.Congressmen want EPA to take severe action and the CEO of VW requested external investigation.

lixibao

time2 2'46
many oncologists prescribe off-label drugs,but this does not show differences in effects of treatment.However,this trail is not accurate.
time3 2'23
the off-label drugs will help the mutation.and if this trail succeed,the off-label personalized drugs can be generally used by oncologists.
time4 2'51
nanparticles can reach specific part of the body,their membrane protein protect them from attacked by immune system.they can also fight with bacteria and repair some organs.
time5 2'42
nanparticle is efficient in defending with platelets.many of nanparticles are also detected by immune system.scientists are now looking for a way to cue cancer by using this.
time6 2'05
the earthquake did cause much damage as the researchers previously thought.
obstacle 10'46
VW company reaches the standard of emission by using a efficient device,but its NOx emission is huge.So companies with this diesel need to shift.VW also needs to make investigations to win the trust of customers.

momoxiong0615

SPEAKER:
1.        Defense Secretary is looking at how biological science, can inform the development of technology to save the livers of military personnel.
2.        DARPA’s hope: health, combat forces, battlefield medicine & brain injury
3.        DARPA launched Biological Technologies Office
4.        Ways to head off infectious diseases
TIME 2: 2’22’’41
Personalized cancer drugs are used to many cancer patients those days, however, a randomized clinical trial shows that cancer drug off-label provides no benefit over conventional chemotherapy. Apostolia doesn’t fully agree with the conclusion, she believes the trail has some flaws on: Choosing patients, selecting drugs and even implementing approach.
TIME 3: 1’41’’26
Some people concedes the trial has some defections, some personalized cancer trials are under way. People believe that if those trials have better effect there will be a severe regulatory challenge.
TIME 4: 2’11’’21
Camouflaging nanoparticles to look like cell fragments could help them past the body’s immune, research are led by Zhang. Disguised particles could: 1. Evade detection, 2. Exploit natural properties of platelets. Previously tried has been completed by researcher, but Zhang’s boast the most complete set of membrane protein yet.
TIME 5: 2’09’’10
Body: Zhang’s cloaked nanoparticles have benefit on:
1.        Reducing MRSA bacteria populations in the liver and spleen
2.        Tend to damage blood vessel with platelets
However, still have some questions: small fraction of particles VS majority of them in liver and spleen.
Conclusion: Developing therapies from hybrid nanoparticles will be a long road.
TIME 6: 1’47’’10
THE REST: 41’’32
An 8.3-magnitude earthquake that struck Chile recently damage a telescope, which operated by a US-Brazil collaboration. It also triggers tsunami but doesn’t bring huge damage as a result of timely warnings and evacuation. However, scientists fear that a “Big One” tsunami is still waiting to happen in Chile and they still keep eyes on it.
OBSTACLE: 8’50’’49
1.        In general, VW violates which Act and points how, installs specific software to pass EPA pollution test. And also indicates about how much penalty.
2.        Specific introduce which test prove VW violates the Act, how the test looks like & which type of VW vehicle shows violation and how much more emission they actually have.
3.         What is EPA’s attitude about this incident, should pursue the most severe action possible, and also indicates some suggesting punishing plans.
4.        VW’s inner opinion about the incident, CEO’s apology, orders external investigation, hope can rebuilt costumer’s trust.

momoxiong0615

fadeday 发表于 2015-9-23 10:18
Speaker: (two times)
Paraphrase: bioscience get the attention of Defense Secretary to help military  ...

哈哈，没有关系啦，刚开始大家都是这样的，加油加油

Elaine_Eady

Time 2-3 05:32
off-label trails against cancers have been prevail but also raised some rebuttals. some oncologists acknowledge that even the trials are often seen in therapy, most of them are poorly designed. if they could match the tumours of mutation with prescribed drugs more precisely, the therapy effects might be better.
now the association has announced plans to enroll patients in a precision-medicine trail, which will match patients to more than 20 drugs and upload data on what happened to those patients into a database to compile. one oncologists adds that in the future they would study the genetic and molecular profiles of tumors.

Time 3-5 06:02
scientists have found a way to disguise the drug to evade the body immune system and cure damages in particular part of body more effectively. the membrane they use could sent a “don’t eat me” signal to immune system and the particles also harness the natural abilities to assist the recovery of tissue damage. Z’s team has made experiments to show that this approach is much more effective than conventional therapy approach. But there is still some doubts arguing that that only small fraction of particles are retained means majority of them are destroyed by immune system. Z says they will plan to maker larger amount of drugs to see the effectiveness, and besides, test whether this approach could be used to target cancer cells.

Time 6-rest 03:20
the earthquake struck C has caused tsunami and rise in sea level in M and J, but led to slight damage. the geological fault zone intersect C is regarded as the main reason for this earthquake as well as several former ones. specialists has deployed GPS equipment to measure the currents in a real port and proclaimed that the “big one” is still waiting to happen.

MelodyDu

PartII Speed
Time2 3'56"
Doctors are searching for the personalized drug to treat cancer, but most of those new drugs are off-label.However, patients and doctors are willing to use personalized drugs as they want to save the life. The randomized trailes of drugs seems feasible as they show no different effects to the patients, while the specialist think it's because the trail is poorly designed.

Time3 2'59"
The prescription of off-label drugs can cause regulatory challenge. More trails will be taken to make personalized drugs tested and be used precisely and legally.

Time4 3'45"
The scientists have created a kind of nanoparticle, which can pass the human natural immune system to send the drug to some specific parts, and even play some extra role like protect the vessel. They have those functions because they are covered by part of platelet, which can send the signal to avoid the immune system and can let the nanoparticle be leaded to the hurted part in the body.

Time5 3'09"
The cloaked nanoparticles can carry medicine to the wound and can play the same effect by less medicine.Besides, it can also help the recovery of the hurted blood vessle. But to some particular organ, the nanoparticles still cannot avoid the immune system, and more experiments will be taken on the large animal, even on human, to delelop this technology.

Nini～

Time2:3’20
Personalized drugs which used to cure cancer are have same effect as the chemotherapy.By this i mean,although patient want live,doctors try their best to help,off-lable drugs turn out to be no special effect.

Time3:3’06
The personalized drugs which prescribed drugs under simple similarity decisions would pose a severe regulatory challenge.
oncologist 肿瘤学家 mutation 突变 tumour 肿瘤

Time4:1’48
Researchers have invented a disguised particle which can not only evade the immune system by covered by human membrane,but also transmit drugs directly to certain place which need to be healed.
platelet 血小板

Time5:1’52
The nano particle are obvious effective than conventional method for delivering drug.
Although there are some question about nano particle can get caught by immune system and finally find in spleen or liver,Zhang would text on larger animals to see is it useful to detect cancer.

Time6:2’18
The 8.3 magnitude earthquake struck on Chile coast conducted a serious tsunami make 25 countries get warned.

Time7:11'41

Amberdan611

60-3 科技
【Time 2】392 words 3:38
Now some oncologists use off-label drugs to treat tumors of their parents, howevr, the new drugs are not more effetive than the traditional drugs.
Maybe they want to test the new drugs based on paients' reactions to these drugs, but the method they use is simple and unscientific.
oncologist n.肿瘤科医生 chemotherapy n.化学疗法  tailored adj.定制的  amenable adj.顺从的，经得起检验的
【Time 3】309 words 2:35
L T concedes that, but he thinks there is no better commercial drugs available.
Actually, now plenty of personalized cancer trails has been conducting.
In the future, oncologists will prescribe treatments based on genetic and molecular features of tumors, rahther than on the basis of where the tumors appear in the body.
【Time 4】364 words 2:34
Man-made nanoparticles disguise as parts of blood-cells so that they can escape from attack of immune systems.
The platelet-coated nanoparticles harness unique abilities of platelet.
platelet n.血小板  membrane n.薄膜   cloak v.遮掩    assassin n.暗杀者，刺客
【Time 5】372 words 2:19
Zhang's team proved two things through testing it on rats: one is that nanoparticles reduce bacterias  more effectively than traditional drugs , and also it can migrate to damaged blood vessels.
Certainly, not everyone approve effects of nanoparticles, they thinks stringent tests of body's immune systems are needed.
Zhang expressed that Developing therapies from nanoparticles are bumy road, but it has promising future.
hybrid n.混血，混合   synthetic adj.综合的，假想的
【Time 6+the rest】326 words+158 words 4:33
A 8.2-magnitude earthquake happened in Chile, fortunately, timely warnings and the evacuation of people seem to have limited the harm caused.
Powerful quakes are common in these surrounding areas.
And it's possible that waves could reach more than 1 meter in some areas, so related officers and researchers should attention it.
magnitude n.大小，重要  evacuation  n.撤退  unscathed adj.未受伤的 aftermath n.结果，后果
misalignment：the incorrect arrangement or position of something in relation to something else.
<Geologists think that it would take a 9.0-magnitude shock to relieve the seismic stress that has built up in the region over the last decades. >
【Paraphrase 7】1586 words 12:31
flimsy adj.浅薄的，轻薄的   warranty n.担保，根据  ludicrous=ridiculous  ambient adj.周围的   diesel n.柴油机  algorithm n.柴油机    compliance n.承诺，顺从
Congressman n.国会议员  willfully adv.蓄意地  evade v.躲避  fraudulently adv.欺骗地，不老实地   deceitful adj.欺骗的，不老实的  abide v.容忍，忍受

米夏

TIME2  02'49
TIME3  02'12
TIME4  03'05
TIME5  02'10
TIME6  01'59

Obstacle 07'03''

__Imp

time 2  2’47
time 3  2’19
time 4  2’52
time 5  2’07
time 6  1’48

Obstacle  6'35