Healthy lungs produce a natural antibiotic that protects them from infection by routinely killing harmful bacteria on airway surfaces. People with cystic fibroses, however, are unable to fight off such bacteria, even though their lungs produce normal amounts of the antibiotic. Since the fluid on airway surfaces in the lungs of people with cystic fibrosis bas an abnormally high salt concentration, scientists hypothesize that in high salt environments the antibiotic becomes ineffective at killing harmful bacteria.

Which of the following, if it were obtained as an experimental result, would most decisively undermine the scientists' hypothesis?

• AHealthy lungs in which the salt concentration of the airway-surface fluid has been substantially increased are able to reestablish their normal salt concentration within a relatively short period of time.  
• BThe antibiotic produced by the lungs is effective at killing harmful bacteria even when salt concentrations are below levels typical of healthy lungs.  
• CThe salt concentration of the airway-surface fluid in the lungs of people who suffer from cystic fibrosis tends to return to its former high levels after having been reduced to levels typical of healthy lungs.  
• DThe lungs of people who suffer from cystic fibrosis are unable to fight off harmful bacteria even when the salt concentration is reduced to levels typical of healthy lungs.  
• EThe salt concentration in the airway-surface fluid of people whose lungs produce lower-than-average amounts of the antibiotic is generally much lower than that typical of healthy lungs.