PREP题 关于现在完成时having能否作修饰成分？

154.       (33193-!-item-!-188;#058&006626)

Some patients who do not respond to therapies for depression may simply have received inadequate treatment, having, for example, been prescribed a drug at a dosage too low to be effective or having been taken off a drug too soon.

(A) having, for example, been prescribed a drug at a dosage too low to be effective or having been

(B) having, for example, a drug prescription that was ineffective because the dosage was too low, or being

(C) as, for example, having too low of a dosage of a prescribed drug for it to be effective, or being

(D) when they have, for example, been prescribed too low a drug dosage to be effective, or were

(E) for example, when they have a drug prescription with a dosage too low to be effective, or been

答案a   为什么这里先在完成时可以做修饰成分？