NN 这两个选项的区别是啥？

158. With only 5 percent of the world's population, United States citizens consume 28 percent of its nonrenewable resources, drive more than one-third of its automobiles, and use 21 times more water per capita than Europeans do.

(A)  With

(B)   As

(C)  Being

(D)  Despite having

(E)   Although accounting for

DE的区别是啥？为什么选E不选D呀？

我理解就是having讲不通，没有其他问题