请教OG第235题

excellent

235. Spanning more than fifty years, Friedrich Miiller began his career in an unpromising apprenticeship as a Sanskrit scholar and culminated in virtually every honor that European governments and learned societies could bestow.

(A)Miiller began his career in an unpromising apprenticeship as
(B)Miiller's career began in an unpromising apprenticeship as
(C)Miiller's career began with the unpromising apprenticeship of being
(D)Miiller had begun his career with the unpromising apprenticeship of being
(E)the career of Miiller has begun with an unpromising apprenticeship of

请问正确选项B中begin in是词组吗？in可否被with替换？

万分感谢！

excellent

in an unpromising apprenticeship是什么意思呀？

excellent

抱歉？

我感激你还来不及呢！

但我的意思是in an unpromising apprenticeship中为什么用介词in呢，with为什么不行？

excellent

i see.

thank you all.