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Useful protein drugs, such as insulin, must still be administered by the cumbersome procedure of injection under the skin. If proteins are taken orally, they are digested and cannot reach their target cells. Certain no protein drugs, however, contain chemical bonds that are not broken down by the digestive system. They can, thus, betaken orally.

The statements above most strongly support a claim that a research procedure that successfully accomplishes which of the following would be beneficial to users of protein drugs?

正确答案: A

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OG11-52 (矛盾的怪題)

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发表于 2010-4-19 22:52:35 | 只看该作者 回帖奖励 |倒序浏览 |阅读模式
OG11-52请大家帮忙看看
52. Useful protein drugssuch as insulinmust still be administered by the cumbersome procedure of injection under the skinIf proteins are taken orally, they are digested and cannot reach their target cellsCertain no protein drugshowever, contain chemical bonds that are not broken down by the digestive systemThey canthusbe taken orally

The statements above most strongly support a claim that a research procedure that successfully accomplishes
which of the following would be beneficial to users of protein drugs?

(A)Coating insulin with compounds that are broken down by target cellsbut whose chemical bonds are resistant to digestion
(B)Converting into protein compoundsby procedures that work in the laboratory, the no protein drugs that resist digestion
(C)Removing permanently from the digestive system any substances that digest proteins
(D)Determiningin a systematic way, what enzymes and bacteria are present in the normal digestive system and whether they tend to be broken down within the body
(E)Determining the amount of time each no protein drug takes to reach its target cells
答案A
我用代號簡化問題
P=protein  ~P= non protein
題目說 P不能被口服 因為消化後 P不能送到Cell
~P 可以被口服 因為有Chemical bond抵制消化系統

想問 題目只有談口服 為什麼答案是塗抹 ?
Coating insulin with compound (that are broken down by target cells )
再看黃色部分說 塗抹的Comound 會被Cell破壞 既然破壞了 怎麼還有辦法將insulin送到Cell運作呢?
矛盾呀

求救中........  
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沙发
发表于 2010-4-20 00:04:21 | 只看该作者
这个Coating insulin的意思应该是,外面表层(Coating)是protein/insulin,里面是chemical bonds
应该是我们平时吃的那种胶囊药。
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