Part II: Speed Article 2: Toxin in seafood causes kidney damage in mice at levels considered safe for consumption
[Time 2] Chemical that can accumulate in seafood and is known to cause brain damage is also toxic to the kidneys, but at much lower concentrations. The findings, which come from a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN), suggest that officials may need to reconsider what levels of the toxin are safe for human consumption.
The world's oceans contain algae that produce certain chemicals that can be harmful to humans and other living creatures. Many of these chemicals are considered neurotoxins because they cause damage to the brain. The neurotoxin domoic acid, also called "Amnesic Shellfish Poisoning," is a very stable, heat resistant toxin that is becoming more prominent in coastal regions, likely due to environmental changes. It can accumulate in mussels, clams, scallops, and fish, and the FDA has set a legal limit of domoic acid in seafood based primarily on its adverse neurological effects.
Because domoic acid is cleared from the body by the kidneys, P. Darwin Bell, PhD, Jason Funk, PhD (Medical University of South Carolina), and their colleagues looked to see if the toxin might also have detrimental effects on these organs. By giving mice varying doses of domoic acid and the assessing animals' kidney health, the team found that the kidney is much more sensitive to this toxin than the brain.
"We have found that domoic acid damages kidneys at concentrations that are 100 times lower than what causes neurological effects," said Dr. Bell. "This means that humans who consume seafood may be at an increased risk of kidney damage possibly leading to kidney failure and dialysis." While the findings need to be verified in humans, the researchers would like to see increased awareness and monitoring of domoic acid levels in all seafood. They say that the FDA may also need to reconsider the legal limit of domoic acid in food due to its kidney toxicity.
【319】 Source:Science Daily http://www.sciencedaily.com/releases/2014/02/140207083619.htm
Article 3: Vultures Know Where Animals Go to Die
[Time 3] The word vulture conjures up visions of boughs laden with crook-neck birds or silhouettes circling in the sky, patiently waiting for death to come to some poor creature. We say “the vultures are circling” to signal that someone is in danger of failing and their competitors are getting ready to swoop in. It turns out that these popular depictions of the world’s most unloved birds are pretty accurate. Vultures really are … well, vultures.
For decades, scientists believed that the vultures in Africa’s Serengeti-Mara ecosystem followed the most abundant food supply—the 1.3 million wildebeest migrating between Tanzania’s Serengeti National Park and Kenya’s Masai Mara National Reserve. But it turns out that vultures aren’t concerned with how many wildebeest are in a given area. Instead, vultures haunt areas where animals are more likely to die.
Vultures are the only obligate scavengers, and they feed primarily on the decaying flesh of animals that died as a result of starvation or disease. The birds have to be able to scan large areas and quickly detect carrion before it is snatched up by hyenas or jackals or decomposed by microbes. Because of their efficient, low-energy soaring flight, vultures can forage over extremely large areas, but researchers didn’t understand how the birds decided where to search.
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[Time 4] To learn how vultures select habitat, Corinne Kendall of Columbia University and her colleagues outfitted 39 birds from three vulture species with GPS transmitters and tracked their whereabouts over the course of several months.
Wildebeest are abundant in the study region throughout the year, but the vultures’ behavior varied with the season. Members of all three species followed the herds only during the dry season—that’s when wildebeest are more likely to die from starvation and drowning.
During the wet season, birds from two of the vulture species preferred to hang out in relatively dry, brown areas. Since rainfall and the availability of edible plants have major impacts on the survival of wildebeest and other ungulates, these parched landscapes are where animals are likely to die.
Focusing their attention on death traps rather than following the migrating herds might not be a great long-term survival strategy, unfortunately. Conservationists are concerned that vultures apparently rely on resident ungulate species during the wet season. Those species are rapidly declining throughout Kenya and in particular in the Masai Mara National Reserve. Food availability is important to a vulture’s survival—especially a chick’s. Two of the species in the study, the White-backed vulture and Ruppell’s vulture, have been up-listed to endangered by the IUCN Red List, while the third species, the Lappet- faced vulture, remains vulnerable.
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Source:Slate http://www.slate.com/blogs/wild_things/2014/02/04/vultures_know_where_animals_go_to_die_feeding_strategies_by_season.html
Article 4: Sail-Backed Dimetrodon Had a Nasty Bite by Brian Switek
[Time 5]
Dimetrodon had a mouth full of novelty. Most conspicuous were several different tooth types in the sail-backed protomammal’s jaws – incisor-like teeth for gripping, stabbing canines, recurved rear teeth for shearing through flesh, and even hidden teeth on the roof of the mouth to pin struggling prey. This combination of features, shared by other members of the sphenacodontid group to which Dimetrodon belonged, originated with such predators as they thrived between 298 and 272 million years ago. And particular species of Dimetrodon even added a new wrinkle to the enamel-based armaments. As described by University of Toronto Mississauga paleontologists Kirstin Brink and Robert Reisz in a new Nature Communications paper, Dimetrodon is the earliest known land-stalking carnivore to have bitten through flesh with serrated teeth.
At a glance, the skulls of Dimetrodon look quite similar. Their main difference is in size. But the teeth of Dimetrodon are a different story. Details in enamel and dentine, Brink and Reisz report, distinguish three different kinds of cutting edges that distinguish smooth-toothed biters from those capable of a saw-edged chomp.
The oldest and smallest species in the study, Dimetrodon milleri, had teeth with straight cutting edges. Sharp, sure, but not especially well-suited to cutting through skin and muscle. By the time of the later, larger Dimetrodon limbatus, though, these carnivores had evolved small serrations in the enamel along the cutting edges of some of the teeth. The teeth of Dimetrodon grandis were even more specialized for cutting. Teeth in this last and largest species of Dimetrodon had prominent denticles along the slicing surface that created a serrated edge similar to that of predatory dinosaurs. Dimetrodon just happened to evolve “ziphodont” teeth about 40 million years earlier. 【287】
[Time 6]
While the three species of Dimetrodon in the study don’t represent a direct evolutionary line, the connection between true serrated teeth and larger body size hint at an ancient arms race between competing predators and their prey.
Dimetrodon wasn’t the only predator around in the Early Permian. Other sphenacodontids, some with very similar skull anatomy, were after the same pool of protomammals, reptiles, and amphibians. This could have driven Dimetrodon to take up a different diet, Brink and Reisz hypothesize, and the changes to their teeth and body size hint that these distant cousins of ours were targeting larger prey with tough hides.
Big, serrate-toothed Dimetrodon evolved at a time when their herbivorous victims were also becoming larger. Barrel-bodied, pin-headed protomammals called caseids proliferated during this time, Brink and Reisz point out, and the sail-backed edaphosaurids, as well as amphibians called diadectids, also underwent an increase in body size. Damaged bones show that Dimetrodon weren’t above eating their own kind, either, and so it’s possible that the serrated teeth of species such as Dimetrodon grandis gave these carnivores the literal edge they needed to expand their menu options.
For now, though, the connections between body size, serrated teeth, competition, and prey availability remain murky. Brink and Reisz stress that further testing and investigation is needed to understand this new aspect of a familiar, but still mysterious relative of ours. From tooth to sail, we’re still getting to know Dimetrodon.
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Source:Nationalgeographic http://phenomena.nationalgeographic.com/2014/02/07/sail-backed-dimetrodon-had-a-nasty-bite/
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