Healthy lungs produce a natural antibiotic that protects them from infection by routinely killing harmful bacteria on airway surfaces. People with cystic fibrosis, however, are unable to fight off such bacteria, even though their lungs produce normal amounts of the antibiotic. The fluid on airway surfaces in the lungs of people with cystic fibrosis has an abnormally high salt concentration; accordingly, scientists hypothesize that the high salt concentration is what makes the antibiotic ineffective.
Which of the following, if true, most strongly supports the scientists' hypothesis?
The hypothesis is about the effects of high salt concentration vs. normal salt concentration. B talks about "an unusually low concentration of salt", and therefore is irrelevant.
IMO, unlike in GMAT Grammar, generally it's probably not a good way of practicing to try "what-if" changes on answer choices in GMAT CR. It unnecessarily complicate sometimes already complicated questions, and may even cause more confusion at times.